Prevalence of Rose Questionnaire Angina and its Association with Coronary Heart Disease Risk Factors in Tehran, IR.Iran

Background: Rose questionnaire is a standard mean for diagnosing angina pectoris in epidemiological study. The present study was done to determine the prevalence of angina pectoris according to Rose questionnaire for chest pain, and to investigate the association of angina with several coronary hearh disease risk factors in Tehran urban population (district-13) during 1999 to 2000. Methods: 6028 person including 3492 women (58%) and 2536 men (42%) aged 30 years and above participated in a cohort study of "Tehran Lipid and Glucose Study". they were screened for hypertension, smoking status, hypercholestrolemia, low high-density lipoprotein cholesterol, obesity, diabetes mellitus and impaired glucose tolerance. A questionnaire including personal information (age, educational attainment), the use of medications for hypertension, diabetes mellitus, and dyslipidemia and standard Rose questionnaire were filled.   Results: Age-Adjusted prevalence rate of angina according to Rose questionnaire was 12. 8 % in women (95% CI, 11.7 to 13.9) and 10. l % (8.8-11.2) in men. The prevalence of angina was higher in women than in men at each age group, with an increase in rate from the youngest to the oldest age group. The prevalence of more severe angina ( definite angina) was about two times of milder angina (possible angina), 11.6% versus 6.4%. In a logestic regression model, hypertension, educational attainment, diabetes, smoking status, and sex were each strongly associated with angina. Hypertension had the strongest and most consistent association with angina. No significant association was found between age, obesity, hypercholestrolemia, HDL and angina. Conclusion: The results indicate that about one tenth of adult population are reporting chest pain. The present study is imited by its cross-sectional design and the relation of angina future coronary heart disease events should be assessed in follow-up of "Tehran Lipid and Glucose Study" population.